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=== '''TNM Staging (AJCC 8th edition§)''' === * '''Primary tumour (T) (male and female)''' ** TX: Primary tumor cannot be assessed ** T0: No evidence of primary tumor ** '''Ta: Non-invasive papillary, polypoid, or verrucous carcinoma''' ** '''Tis: Carcinoma in situ''' ** '''T1: invades subepithelial connective tissue''' ** '''T2: invades''' **# '''Corpus spongiosum OR''' **# '''Periurethral muscle''' ** '''T3: invades''' **# '''Corpus cavernosum''' '''OR''' **# '''Anterior vagina''' ** '''T4: invades other adjacent organs (e.g. invasion of bladder wall)''' * '''Urothelial carcinoma of the prostate''' ** '''pTis: carcinoma in situ of the prostatic urethra, periurethra or ducts''' *** '''Tis pu: Carcinoma in situ, involvement of prostatic urethra''' *** '''Tis pd: Carcinoma in situ, involvement of prostatic ducts''' ** '''pT1: invasion of prostatic urethral subepithelial connective tissue''' ** '''pT2: invasion of prostatic stroma''' *** '''In the bladder cancer TNM staging system, only patients with prostatic stromal invasion, either direct or indirect, are considered to have T4a-staged bladder cancer disease''' *** '''Extension of the tumor into the prostatic urethra without stromal invasion is currently classified under the prostatic urethral section, not bladder''' ** '''pT3''': invasion of periprostatic fat or bladder neck (extraprostatic extension) ** '''pT4''': invasion of adjacent organs (example: bladder wall, rectal wall) * '''Regional lymph nodes (N) (similar to bladder)''' ** Nx: lymph nodes cannot be assessed ** N0: no lymph node metastasis ** N1: single regional lymph node in the true pelvis *** True pelvis lymph nodes (5) ***# Perivesical ***# Obturator ***# Internal iliac (hypogastric) ***# External iliac ***# Presacral lymph nodes ** N2: multiple regional lymph node metastases in the true pelvic ** N3: lymph node metastasis to the common iliac lymph nodes * Distant metastasis (M) ** MX: Presence of distant metastasis cannot be assessed ** M0: No distant metastasis ** M1: Distant metastasis
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