Editing Infections: Antibiotics (section)

===Cephalosporins===
*'''In general, as a group, activity is high against Enterobacteriaceae and poor against enterococci'''
*First-generation cephalosporins have greater activity against gram-positive organisms, as well as common uropathogens such as E. coli and Klebsiella pneumoniae, whereas second-generation cephalosporins have activity against anaerobes. Third-generation cephalosporins are more reliably active against community-acquired and nosocomial gram-negative organisms than other β-lactam antimicrobials.
*Use of these broad-spectrum agents should be limited complicated infections and situations in which parenteral therapy is required and resistance to standard antimicrobial agents is likely.
*'''Safe for use during pregnancy'''
*'''Ceftriaxone is contraindicated in neonates'''