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Intestinal Segments and Urinary Diversion
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=== Classification (2) === *'''Mechanical vs. antibiotic''' ==== Mechanical (whole-gut irrigation) ==== * '''<span style="color:#ff0000">Reduces the amount of feces/total number of bacteria but not their concentration''' * '''Can be done with polyethylene glycol (PEG)–electrolyte solution''' ===== Efficacy ===== *'''<span style="color:#ff00ff">2011 Cochrane review: Mechanical bowel preparation for elective colorectal surgery''' ** '''18 trials with 5,805 participants were analyzed''' ** '''No difference in anastomotic leakage or wound infection rates; important to note that many of these studies involved peri-operative intravenous antibiotics and likely crucial in keeping the complication rate low''' ** '''[https://pubmed.ncbi.nlm.nih.gov/21901677/ Güenaga, Katia F., Delcio Matos, and Peer Wille‐Jørgensen."Mechanical bowel preparation for elective colorectal surgery." Cochrane Database of Systematic Reviews 9 (2011)]''' * '''No studies have adequately assessed the safety of omitting mechanical bowel preparation in urologic reconstructive surgery''' ===== Contraindications (5): ===== # '''Obstructed bowel''' # '''Unstable cardiovascular system''' # '''Congestive heart failure''' # '''Cirrhosis''' # '''Severe CKD''' ===== Adverse Events ===== *'''Hypokalemia''' **'''Vigorous bowel cleansing, even with Go-Lytely or other electrolyte solutions, will often result in low potassium.''' *** '''Characteristic signs include muscular weakness with poor respiratory effort causing decreased ventilation in the presence of a normal chest x-ray.''' *'''Diarrhea''' ==== Antibiotic ==== * '''<span style="color:#ff0000">Reduces the bacterial concentration''' * '''<span style="color:#ff0000">PERIoperative IV antibiotics appear to be the most important means of preventing infectious complications of intestinal surgery.''' **'''Systemic antibiotics must be given before the operative event if they are to be effective.''' ***A randomized trial in elective colorectal surgery found that PREoperative antibiotics did not reduce the risk of clinical infections[https://www.ncbi.nlm.nih.gov/pubmed/17443852 §] ** '''If perioperative antibiotics are given, they should be effective against anaerobes because it is complications from these organisms against which perioperative antibiotics appear to be particularly effective.''' ===== Adverse Events ===== *'''Diarrhea''' *'''Pseudomembranous enterocolitis''' ** '''Treatment involves the administration of vancomycin or metronidazole and discontinuance of other antibiotics that the patient is receiving'''
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