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Management of Localized and Locally Advanced Disease
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== Answers == # What are the treatment options for a patient with localized kidney cancer? ## Radical nephrectomy ## Partial nephrectomy ## Thermal ablation ## Surveillance # Which patients should be preferentially treated with partial over radical nephrectomy? ## Clinical T1a when technically feasible ## Solitary kidney (functional or anatomical) ## Bilateral tumours ## Multiple tumours ## Familial RCC syndrome ## Pre-existing CKD ## Risk of ESRD after RN ## Proteinuria # When should nephrology referral be considered prior to surgical management of RCC? ## Confirmed proteinuria ## Diabetes with pre-existing CKD ## eGFR < 45 ## Expected eGFR < 30 after intervention # What are the indications of intervention in a patient on surveillance for a small renal mass? ## Tumour size >3cm ## Stage progression ## Growth kinetics (>5mm/year) ## Patient preference # What clinical findings are suggestive of IVC involvement of a renal malignancy? ## Lower extremity edema ## Non-reducing or right-sided varicocele ## Dilated superficial abdominal veins ## Right atrial mass ## Proteinuria ## Pulmonary embolus ## Non function of the involved kidney # What is the differential diagnosis of a large, invasive upper quadrant abdominal mass? ## Locally advanced RCC ## Urothelial Ca ## Adrenal Ca ## Sarcoma ## Lymphoma # As per the CUA guidelines on follow-up after treatment for RCC, when is abdominal imaging indicated in a patient with pT1a disease? #* 24 and 60 months
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