CUA: Neurogenic Lower Urinary Tract Dysfunction (2019): Difference between revisions

Created page with " '''See Original Guideline''' ===== '''Defintions''' ===== * '''Definition of neurogenic lower urinary tract dysfunction (NLUTD): lower urinary tract dysfunction due to disturbance of the neurological control mechanism''' ** This broad definition is used to describe a multitude of conditions of varying severity ===== '''Causes of NLUTD''' ===== * '''Neurological conditions commonly associated with LUT dysfunction (3):''' *# '''Multiple sclerosis (MS)''' *# '''Spina..."
 
No edit summary
Line 3: Line 3:
'''See Original Guideline'''
'''See Original Guideline'''


===== '''Defintions''' =====
== Definitions ==


* '''Definition of neurogenic lower urinary tract dysfunction (NLUTD): lower urinary tract dysfunction due to disturbance of the neurological control mechanism'''
* '''Definition of neurogenic lower urinary tract dysfunction (NLUTD): lower urinary tract dysfunction due to disturbance of the neurological control mechanism'''
** This broad definition is used to describe a multitude of conditions of varying severity
** This broad definition is used to describe a multitude of conditions of varying severity


===== '''Causes of NLUTD''' =====
== Causes of NLUTD ==


* '''Neurological conditions commonly associated with LUT dysfunction (3):'''
* '''Neurological conditions commonly associated with LUT dysfunction (3):'''
Line 53: Line 53:
|}
|}


===== '''Risk classification for urological morbidity in NLUTD''' =====
== Risk classification for urological morbidity in NLUTD ==
{| class="wikitable"
{| class="wikitable"
|'''Risk group'''
|'''Risk group'''
Line 87: Line 87:
* '''Patients with SCI, spina bifida, or advanced MS without high-risk features are considered moderate-risk'''
* '''Patients with SCI, spina bifida, or advanced MS without high-risk features are considered moderate-risk'''


===== '''Genitourinary sequelae of NLUTD (SUSU VIU)''' =====
== Genitourinary sequelae of NLUTD ==
 
===='''(SUSU VIU)''' =====


# '''Sepsis'''
# '''Sepsis'''
Line 154: Line 156:
*** Renal function decline can occur up to 45 years after injury
*** Renal function decline can occur up to 45 years after injury


===== '''Autonomic dysreflexia''' =====
== Autonomic dysreflexia ==


* '''Typically occurs in patients with an injury at level T6 or above'''
* '''Typically occurs in patients with an injury at level T6 or above'''
Line 179: Line 181:
** Recent data suggests that intravesical injection of onabotulintoxinA decreases the frequency and severity of AD episodes.
** Recent data suggests that intravesical injection of onabotulintoxinA decreases the frequency and severity of AD episodes.


===== Diagnosis and Evaluation =====
== Diagnosis and Evaluation ==


* '''Mandatory in all patients (3): history and physical exam, urinalysis, PVR'''
* '''Mandatory in all patients (3): history and physical exam, urinalysis, PVR'''
Line 265: Line 267:
* '''See Figure 2 from Original Guideline'''
* '''See Figure 2 from Original Guideline'''


===== '''Management of NLUTD''' =====
== Management of NLUTD ==


* '''The treating clinician should identify patients as either being high-, moderate-, or low-risk, offer the patient appropriate initial therapy, and consider a urological surveillance program as outlined below'''
* '''The treating clinician should identify patients as either being high-, moderate-, or low-risk, offer the patient appropriate initial therapy, and consider a urological surveillance program as outlined below'''
Line 334: Line 336:
**** The bladder should be removed at the time of surgery to reduce the risks of pyocystis, chronic symptomatic cystitis, and malignancy
**** The bladder should be removed at the time of surgery to reduce the risks of pyocystis, chronic symptomatic cystitis, and malignancy


'''Surveillance studies for NLUTD patients in the community setting'''
== Surveillance studies for NLUTD patients in the community setting ==
{| class="wikitable"
{| class="wikitable"
|'''Risk group'''
|'''Risk group'''
Line 363: Line 365:
* We support the use of cystoscopy for the assessment of suspected urethral or bladder pathology. '''We do not support routine surveillance cystoscopy for bladder cancer screening in NLUTD with or without augmentation cystoplasty'''
* We support the use of cystoscopy for the assessment of suspected urethral or bladder pathology. '''We do not support routine surveillance cystoscopy for bladder cancer screening in NLUTD with or without augmentation cystoplasty'''


===== Questions =====
== Questions ==


# List conditions associated with neurogenic lower urinary tract dysfunction.
# List conditions associated with neurogenic lower urinary tract dysfunction.
Line 414: Line 416:
# What is the recommended surveillance in patients with NLUTD?
# What is the recommended surveillance in patients with NLUTD?


===== Answers =====
== Answers ==


# List conditions associated with neurogenic lower urinary tract dysfunction.
# List conditions associated with neurogenic lower urinary tract dysfunction.