Pathophysiology of Erectile Dysfunction: Difference between revisions
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**# '''<span style="color:#ff0000">Blunt perineal or pelvic trauma</span>''' | **# '''<span style="color:#ff0000">Blunt perineal or pelvic trauma</span>''' | ||
**# '''<span style="color:#ff0000">Pelvic irradiation</span>''' | **# '''<span style="color:#ff0000">Pelvic irradiation</span>''' | ||
** '''Atherosclerotic or traumatic arterial occlusive disease''' can decrease perfusion pressure and arterial flow to the sinusoidal spaces, increasing time to maximal erection and decreasing the rigidity of the erect penis | ** '''Atherosclerotic or traumatic arterial occlusive disease''' can decrease perfusion pressure and arterial flow to the sinusoidal spaces, increasing time to maximal erection and decreasing the rigidity of the erect penis | ||
***In most patients with arteriogenic ED secondary to atherosclerosis, the impaired penile perfusion is a component of the generalized atherosclerotic process. | |||
** Lesions in the pudendal arteries are much more common in ED men than in the general population of similar age. | ** Lesions in the pudendal arteries are much more common in ED men than in the general population of similar age. | ||
** Cardiovascular disease is associated with ED. Because the size of the penile artery is smaller compared with coronary arteries, the same level of endothelial dysfunction causes a more significant reduction of blood flow in erectile tissues compared with that in coronary circulation | ** Cardiovascular disease is associated with ED. Because the size of the penile artery is smaller compared with coronary arteries, the same level of endothelial dysfunction causes a more significant reduction of blood flow in erectile tissues compared with that in coronary circulation | ||