Functional: Pharmacological Management of LUTS: Difference between revisions
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====== Tropsium (Trosec) ====== | ====== Tropsium (Trosec) ====== | ||
* '''Metabolism: mainly eliminated unchanged in the urine; not metabolized by the cytochrome P450 enzyme''' | * '''<span style="color:#ff0000">Metabolism: mainly eliminated unchanged in the urine; not metabolized by the cytochrome P450 enzyme</span>''' | ||
** Darifenacin, solifenacin, fesoterodine, tolterodine, and oxybutynin, are all actively metabolized in the liver by the cytochrome P450 enzyme system. Trospium chloride is not metabolized to any significant degree in the liver | ** Darifenacin, solifenacin, fesoterodine, tolterodine, and oxybutynin, are all actively metabolized in the liver by the cytochrome P450 enzyme system. Trospium chloride is not metabolized to any significant degree in the liver | ||
* '''Selectivity:''' no selectivity for muscarinic receptor subtypes. | * '''Selectivity:''' no selectivity for muscarinic receptor subtypes. | ||