AUA: Vesicoureteral Reflux (2017): Difference between revisions

Line 28: Line 28:


=== History and Physical Exam ===
=== History and Physical Exam ===
* '''History'''
* '''<span style="color:#ff0000">History'''
**'''Assess for symptoms of bladder/bowel dysfunction (BBD) including (6):'''
**'''<span style="color:#ff0000">Assess for symptoms of bladder/bowel dysfunction (BBD) including (6):'''
**# '''Urinary frequency and urgency'''
**# '''<span style="color:#ff0000">Urinary frequency and urgency'''
**# '''Prolonged voiding intervals'''
**# '''<span style="color:#ff0000">Prolonged voiding intervals'''
**# '''Daytime wetting'''
**# '''<span style="color:#ff0000">Daytime wetting'''
**# '''Perineal/penile pain'''
**# '''<span style="color:#ff0000">Perineal/penile pain'''
**# '''Holding maneuvers (posturing to prevent wetting)'''
**# '''<span style="color:#ff0000">Holding maneuvers (posturing to prevent wetting)'''
**# '''Constipation/encopresis''' (soiling of underwear with stool by children who are beyond age of toilet training)
**# '''<span style="color:#ff0000">Constipation/encopresis</span>''' (soiling of underwear with stool by children who are beyond age of toilet training)
*** '''BBD''', dysfunctional voiding, dysfunctional elimination syndrome and dysfunctional lower urinary tract symptoms, refer to a common but poorly characterized '''complex of symptoms typically including urinary incontinence, frequency or infrequent voiding, dysuria, UTI, and constipation'''
*** '''<span style="color:#ff0000">Bladder bowel dysfunction (BBD)</span>''', dysfunctional voiding, dysfunctional elimination syndrome and dysfunctional lower urinary tract symptoms, refer to a common but poorly characterized '''<span style="color:#ff0000">complex of symptoms typically including urinary incontinence, frequency or infrequent voiding, dysuria, UTI, and constipation'''
*** '''Untreated BBD associated with:'''
*** '''Untreated BBD associated with:'''
**** '''Increased incidence of breakthrough UTI in children on continuous antibiotic prophylaxis (CAP)'''
**** '''Increased incidence of breakthrough UTI in children on continuous antibiotic prophylaxis (CAP)'''
**** '''Decreased resolution rates of VUR at initial follow-up in children treated with endoscopic surgery'''
**** '''Decreased resolution rates of VUR at initial follow-up in children treated with endoscopic surgery'''
***** '''BBD does not alter surgical resolution rates in children treated with open surgery'''
***** '''BBD does not alter surgical resolution rates in children treated with open surgery'''
* '''Physical exam'''
* '''<span style="color:#ff0000">Physical exam'''
**'''General medical evaluation including measurement of'''  
**'''<span style="color:#ff0000">General medical evaluation including measurement of'''  
***'''Height'''
***'''<span style="color:#ff0000">Height'''
***'''Weight'''
***'''<span style="color:#ff0000">Weight'''
***'''Blood pressure'''
***'''<span style="color:#ff0000">Blood pressure'''


=== Labs ===
=== Labs ===
*'''Serum creatinine'''
*'''<span style="color:#ff0000">Serum creatinine'''
**'''Indications'''
**'''<span style="color:#ff0000">Indications'''
***'''Absolute (1):'''
***'''<span style="color:#ff0000">Absolute (1):'''
****'''Bilateral renal abnormalities'''
****'''<span style="color:#ff0000">Bilateral renal abnormalities'''
***'''Relative'''
***'''Relative'''
****'''Children with VUR but without bilateral renal abnormalities''' to establish an estimate of glomerular filtration rate (GFR) for future reference.
****'''Children with VUR but without bilateral renal abnormalities''' to establish an estimate of glomerular filtration rate (GFR) for future reference.
* '''Urinalysis'''
* '''<span style="color:#ff0000">Urinalysis'''
**Evaluate for proteinuria and bacteriuria''';''' if the urinalysis indicates infection, a urine culture and sensitivity is recommended
**Evaluate for proteinuria and bacteriuria''';''' if the urinalysis indicates infection, a urine culture and sensitivity is recommended


=== Imaging ===
=== Imaging ===
* '''Recommended (1)''':
* '''<span style="color:#ff0000">Recommended (1)''':
**'''Renal ultrasound'''  
**'''<span style="color:#ff0000">Renal ultrasound'''  
***VUR and UTI may affect renal structure and function
***VUR and UTI may affect renal structure and function
* '''Optional (1)'''
* '''<span style="color:#ff0000">Optional (1)'''
**'''DMSA''' (technetium-99m-labeled dimercaptosuccinic acid)  
**'''<span style="color:#ff0000">DMSA</span>''' (technetium-99m-labeled dimercaptosuccinic acid)  
***'''To assess the status of the kidneys for scarring and function'''
***'''To assess the status of the kidneys for scarring and function'''
**** '''Children with higher grades of VUR (i.e. grades III to V) are at greater risk of having renal cortical abnormalities.'''
**** '''Children with higher grades of VUR (i.e. grades III to V) are at greater risk of having renal cortical abnormalities.'''
**** DMSA scanning can be useful to identify pre-existing abnormalities.
**** DMSA scanning can be useful to identify pre-existing abnormalities.
== Initial Management of the Child with VUR ==
== Initial Management of the Child with VUR ==