Pediatrics: Vesicoureteral Reflux: Difference between revisions

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== Embryology of the Ureterovesical Junction ==
== Embryology of the Ureterovesical Junction ==


* If the ureteric bud reaches the urogenital sinus too late (because of budding late), insufficient rotation occurs, resulting in an ectopic ureter
* '''Primary vesicoureteral reflux is due to early budding that results in a lateral and high insertion in the bladder'''
* '''A ureteral bud that is laterally (cranially) positioned from a normal takeoff at the trigone offers an embryologic explanation for primary reflux,''' whereas those inferiorly (caudally) positioned are often obstructed.
**'''A ureteral bud that is laterally (cranially) positioned from a normal takeoff at the trigone offers an embryologic explanation for primary reflux,''' whereas those inferiorly (caudally) positioned are often obstructed.
*'''Ectopic ureter is due to late budding''' (the ureteric bud reaches the urogenital sinus too late) that results in insufficient rotation and ectopic ureter


== Functional Anatomy of the Antireflux Mechanism ==
== Functional Anatomy of the Antireflux Mechanism ==