Germ Cell Tumours: Difference between revisions

Line 722: Line 722:


* ≈15-20% of patients with seminoma have CS II disease at diagnosis; 70% of these patients have CS IIA and IIB.
* ≈15-20% of patients with seminoma have CS II disease at diagnosis; 70% of these patients have CS IIA and IIB.
* '''CSIIA:'''
* '''<span style="color:#ff0000">CSIIA:</span>'''
** '''CUA: Dog-leg radiotherapy (25-35 Gy) preferred over first-line chemotherapy (BEP×3 or EP×4)'''
** '''CUA: Dog-leg radiotherapy (25-35 Gy) preferred over first-line chemotherapy (BEP×3 or EP×4)'''
** '''AUA: radiotherapy or chemotherapy'''
** '''AUA: radiotherapy or chemotherapy'''
* '''CSIIB:'''
* '''<span style="color:#ff0000">CSIIB:</span>'''
** '''CUA: depending on bulk of disease and location of lymph nodes, radiation or chemotherapy [good risk chemotherapy BEP×3 or EP×4] can be used.'''  
** '''CUA: depending on bulk of disease and location of lymph nodes, radiation or chemotherapy [good risk chemotherapy BEP×3 or EP×4] can be used.'''  
*** '''First-line chemotherapy is recommended for bulky (>3 cm) and/or multifocal retroperitoneal metastases'''
*** '''First-line chemotherapy is recommended for bulky (>3 cm) and/or multifocal retroperitoneal metastases'''