Bladder Cancer: Diagnosis and Evaluation: Difference between revisions
Urology4all (talk | contribs) m Urology4all moved page Diagnosis and Evaluation of Bladder Cancer to Bladder Cancer: Diagnosis and Evaluation without leaving a redirect |
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*** '''<span style="color:#ff0000">Due to high specificity, a positive reading regardless of cystoscopic or radiographic findings suggests the existence of malignancy in the vast majority of patients.</span>''' | *** '''<span style="color:#ff0000">Due to high specificity, a positive reading regardless of cystoscopic or radiographic findings suggests the existence of malignancy in the vast majority of patients.</span>''' | ||
**** In a study of patients with a negative workup (cystoscopy and upper tract imaging) with a persistently positive cytology, ≈40% were found to have genitourinary cancer within 24 months | **** In a study of patients with a negative workup (cystoscopy and upper tract imaging) with a persistently positive cytology, ≈40% were found to have genitourinary cancer within 24 months | ||
** '''Atypical cytology''' | ** '''Approximately 30% of patients with isolated CIS will present with gross hematuria''' | ||
***Study design: Retrospective cohort study | |||
***Population: 155 patients diagnosed with isolated primary high grade carcinoma in situ at a tertiary center from 1990 to 2008 who underwent transurethral resection followed by intravesical bacillus Calmette-Guerin therapy | |||
***Results | |||
****Presenting symptoms | |||
*****Asymptomatic, micro hematuria (23%) | |||
*****Gross hematuria (34%) | |||
*****Voiding symptoms (irritative or obstructive (30%) | |||
*****Unknown (14%) | |||
***[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226045/ Chade, Daher C., et al.] "Clinical outcomes of primary bladder carcinoma in situ in a contemporary series." ''The Journal of urology'' 184.1 (2010): 74-80. | |||
**'''Atypical cytology''' | |||
*** '''15% have cancer''' | *** '''15% have cancer''' | ||
** '''<span style="color:#ff0000">2021 CUA NMIBC Guidelines: Either voided or bladder washing urine cytology should be performed as an adjunct to cystoscopy in the initial diagnosis of NMIBC</span>''' | ** '''<span style="color:#ff0000">2021 CUA NMIBC Guidelines: Either voided or bladder washing urine cytology should be performed as an adjunct to cystoscopy in the initial diagnosis of NMIBC</span>''' | ||