AUA: Upper Tract Urothelial Carcinoma (2023): Difference between revisions
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*#*'''<span style="color:#ff0000">To identify known hereditary risk factors for familial diseases associated with Lynch Syndrome</span>''' | *#*'''<span style="color:#ff0000">To identify known hereditary risk factors for familial diseases associated with Lynch Syndrome</span>''' | ||
* '''<span style="color:#ff0000">Laboratory (2):</span>''' | * '''<span style="color:#ff0000">Laboratory (2):</span>''' | ||
*# '''<span style="color:#ff0000">Selective ipsilateral upper tract cytology</span>''' | *# '''<span style="color:#ff0000">Selective ipsilateral upper tract urine cytology</span>''' | ||
*# '''<span style="color:#ff0000">Estimated GFR/Serum Cr</span>''' | *# '''<span style="color:#ff0000">Estimated GFR/Serum Cr</span>''' | ||
* '''<span style="color:#ff0000">Imaging (1):</span>''' | * '''<span style="color:#ff0000">Imaging (1):</span>''' | ||
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=== Laboratory === | === Laboratory === | ||
* '''<span style="color:#ff0000">Selective ipsilateral upper tract cytology</span>''' | * '''<span style="color:#ff0000">Selective ipsilateral upper tract urine cytology</span>''' | ||
** '''Provides supplemental histologic data to tumor biopsies''' | ** '''Provides supplemental histologic data to tumor biopsies''' | ||
***'''High-grade cytology in the setting of low-grade biopsy findings indicates the likely presence of higher-risk features (e.g., high-grade tumor) missed on biopsy sampling.''' | ***'''High-grade cytology in the setting of low-grade biopsy findings indicates the likely presence of higher-risk features (e.g., high-grade tumor) missed on biopsy sampling.''' | ||
**Urine cytology is reported according to | **Urine cytology is reported according to 7 categories (Paris System): | ||
***Nondiagnostic | |||
***Negative for high-grade urothelial carcinoma | |||
***Atypical urothelial cells | |||
***Suspicious for high-grade urothelial carcinoma | |||
***High-grade urothelial carcinoma | |||
***Low-grade urothelial neoplasm | |||
***Other malignancies | |||
**'''Can be obtained either as barbotage (saline irrigation and aspiration) or by saline irrigation with passive collection (washings)''' | **'''Can be obtained either as barbotage (saline irrigation and aspiration) or by saline irrigation with passive collection (washings)''' | ||
**Preferred to a voided urinary specimen due to | **Preferred to a voided urinary specimen due to | ||