UrologySchool.com

AUA: Upper Tract Urothelial Carcinoma (2023): Difference between revisions

← Older editNewer edit →
VisualWikitext
Line 87: Line 87:
**#Other malignancies
**#Other malignancies
*'''<span style="color:#ff0000">Assessment of renal function</span>'''
*'''<span style="color:#ff0000">Assessment of renal function</span>'''
**Initial decisions regarding operative approach and administration of systemic therapy are based on baseline renal function and estimated post-operative estimated glomerular filtration rate (eGFR).  
**Can help with patient counseling, strategizing treatment sequence (operative approach and administration of systemic therapy), and determination of downstream risks of CKD and potential dialysis.
***Recommended tests include serum creatinine to calculate an eGFR  
****For more refined evaluation, split function testing such as with differential renal scan or CT volumetric studies may be considered.
***The two formulas for monitoring eGFR commonly reported in the contemporary literature at this time are the [https://www.mdcalc.com/calc/76/mdrd-gfr-equation Modification of Diet in Renal Disease] and [https://www.mdcalc.com/calc/3939/ckd-epi-equations-glomerular-filtration-rate-gfr CKD – Epidemiology Collaboration (CKD-EPI)] equations.
***The two formulas for monitoring eGFR commonly reported in the contemporary literature at this time are the [https://www.mdcalc.com/calc/76/mdrd-gfr-equation Modification of Diet in Renal Disease] and [https://www.mdcalc.com/calc/3939/ckd-epi-equations-glomerular-filtration-rate-gfr CKD – Epidemiology Collaboration (CKD-EPI)] equations.


Line 227: Line 229:
***'''Toxicities associated with surgical treatment'''
***'''Toxicities associated with surgical treatment'''
****'''Risk of post-NU CKD or dialysis.'''
****'''Risk of post-NU CKD or dialysis.'''
***** '''Initial decisions regarding operative approach and administration of systemic therapy are based on patients’ baseline renal function and their estimated post-operative estimated glomerular filtration rate (eGFR).'''
*******
******Results of renal function investigations can help with patient counseling, strategizing treatment sequence, and determination of downstream risks of CKD and potential dialysis.
******'''Patients with UTUC should, therefore, undergo an assessment of baseline renal function and, for individuals who are scheduled to undergo NU and especially those who may require perioperative systemic treatment, an estimation of post-operative renal function should be made.'''
*******Recommended tests include serum creatinine to calculate an eGFR and, at the clinician’s discretion for more refined evaluation, split function testing such as with differential renal scan or CT volumetric studies.
*******'''Predictive factors for post-operative development of CKD or progression of pre-existing CKD include (8):'''
*******'''Predictive factors for post-operative development of CKD or progression of pre-existing CKD include (8):'''
*******#'''Older age'''
*******#'''Older age'''
Retrieved from "https://urologyschool.com/wikiuro/index.php/AUA:_Upper_Tract_Urothelial_Carcinoma_(2023)"