Hormonal Therapy: Difference between revisions
Urology4all (talk | contribs) |
Urology4all (talk | contribs) |
||
| Line 44: | Line 44: | ||
=== Approaches for Androgen Axis Blockage === | === Approaches for Androgen Axis Blockage === | ||
* Classified into (4): | * '''Classified into (4): inhibit source, stimulation, synthesis, and receptor''' | ||
*# '''Ablation of sources (bilateral orchiectomy)''' | *# '''Ablation of sources (bilateral orchiectomy)''' | ||
*# '''Inhibition of stimulation i.e. luteinizing hormone–releasing hormone (LHRH/GnRH) and/or LH release (estrogen, LHRH agonists/antagonists)''' | *# '''Inhibition of stimulation i.e. luteinizing hormone–releasing hormone (LHRH/GnRH) and/or LH release (estrogen, LHRH agonists/antagonists)''' | ||
*# '''Inhibition of synthesis (ketoconazole, abiraterone)''' | *# '''Inhibition of synthesis (ketoconazole, abiraterone)''' | ||
*# '''Androgen-receptor antagonists | *# '''Androgen-receptor antagonists i.e anti-androgens''' '''(cyproterone acetate, flutamide, bicalutamide, enzalutamide, apalutamide, daralutamide)''' | ||
==== Ablation of Androgen Sources ==== | ==== Ablation of Androgen Sources ==== | ||