Infertility: Nonsurgical Management: Difference between revisions

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 == General Principles'''§''' ==
-* '''Advise couples with advanced paternal age (≥40) that there is an increased risk of adverse health outcomes for their offspring.'''
-** '''Effects of male age on reproductive function'''
-*** Reproductive function
-*** Sexual function
-*** Testicular morphology
-*** Semen parameters (except sperm concentration, semen parameters decrease as age increases)
-*** Infections of the accessory glands
-*** Vascular disease
-*** Genetics (sperm aneuploidies, aneuploidies in off-spring, sperm DNA integrity, telomeres, epigenetics)
-*** Fertility
-*** Miscarriage
-*** C-section
-*** Pre-eclampsia
-*** Trophobalst disease
-*** Preterm birth
-*** Adverse outcome in offspring
-**Genetic counseling may be appropriate for couples with advanced paternal age to discuss the magnitude of these risks
 *May use aromatase inhibitors (AIs), hCG, selective estrogen receptor modulators (SERMs), or a combination thereof for infertile men with low serum testosterone
 *For the male interested in current or future fertility, testosterone monotherapy should not be prescribed.