Stones: Evaluation and Medical Management: Difference between revisions
Urology4all (talk | contribs) |
Urology4all (talk | contribs) |
||
| Line 146: | Line 146: | ||
=== Extensive Diagnostic Evaluation === | === Extensive Diagnostic Evaluation === | ||
* ''' | * '''<span style="color:#ff0000">Consists of one or two 24-hour urine collections obtained on a random diet[https://pubmed.ncbi.nlm.nih.gov/24857648/ ★]</span>''' | ||
**'''<span style="color:#ff0000">24-hour urine collections analyzed at minimum for (9): [https://pubmed.ncbi.nlm.nih.gov/24857648/ ★]</span>''' | |||
***'''<span style="color:#ff0000">Volume</span>''' | |||
***'''<span style="color:#ff0000">pH</span>''' | |||
***'''<span style="color:#ff0000">Creatinine</span>''' | |||
***'''<span style="color:#ff0000">Sodium</span>''' | |||
***'''<span style="color:#ff0000">Potassium</span>''' | |||
***'''<span style="color:#ff0000">Calcium</span>''' | |||
***'''<span style="color:#ff0000">Oxalate</span>''' | |||
***'''<span style="color:#ff0000">Uric acid</span>''' | |||
***'''<span style="color:#ff0000">Citrate</span>''' | |||
*'''Indications for a metabolic stone evaluation''' | *'''Indications for a metabolic stone evaluation''' | ||
*'''<span style="color:#ff0000">AUA (7):</span>''' | **'''<span style="color:#ff0000">AUA (7):[https://pubmed.ncbi.nlm.nih.gov/24857648/ ★]</span>''' | ||
*#'''<span style="color:#ff0000">Recurrent stone formers</span>''' | **#'''<span style="color:#ff0000">Recurrent stone formers</span>''' | ||
*#'''<span style="color:#ff0000">Family history of stone disease</span>''' | **#'''<span style="color:#ff0000">Family history of stone disease</span>''' | ||
*#'''<span style="color:#ff0000">Malabsorptive intestinal disease or resection</span>''' | **#'''<span style="color:#ff0000">Solitary kidney</span>''' | ||
*#'''<span style="color:#ff0000"> | **#'''<span style="color:#ff0000">Malabsorptive intestinal disease or resection</span>''' | ||
*#'''<span style="color:#ff0000"> | **#'''<span style="color:#ff0000">Obesity</span>''' | ||
*#'''<span style="color:#ff0000">Medical conditions predisposing to stones (e.g., RTA Type 1, primary hyperparathyroidism, gout, diabetes mellitus type)</span>''' | **#'''<span style="color:#ff0000">Recurrent UTIs</span>''' | ||
* | **#'''<span style="color:#ff0000">Medical conditions predisposing to stones (e.g., RTA Type 1, primary hyperparathyroidism, gout, diabetes mellitus type)</span>''' | ||
*Included in other lists | **Included in other lists | ||
*# Pathological skeletal fractures | **# Pathological skeletal fractures | ||
*# Osteoporosis | **# Osteoporosis | ||
*# Infirm health (unable to tolerate repeat stone episodes) | **# Infirm health (unable to tolerate repeat stone episodes) | ||
*# Anatomic abnormalities | **# Anatomic abnormalities | ||
*# Stones composed of cystine, uric acid, and struvite | **# Stones composed of cystine, uric acid, and struvite | ||
*# Children should generally be evaluated because of concerns about renal damage and long-term sequelae of stone recurrence | **# Children should generally be evaluated because of concerns about renal damage and long-term sequelae of stone recurrence | ||
* '''Significant aberrations in total creatinine excretion from estimated volumes (males 20-25mg/kg and females 15-20mg/kg in 24 hours) imply incomplete collection, overcollection, greater than expected muscle mass, or less than expected muscle mass''' | * '''Significant aberrations in total creatinine excretion from estimated volumes (males 20-25mg/kg and females 15-20mg/kg in 24 hours) imply incomplete collection, overcollection, greater than expected muscle mass, or less than expected muscle mass''' | ||
** For abnormally collected 24 hour urine collections, can divide metabolite excretion by creatinine excretion to compare collections | ** For abnormally collected 24 hour urine collections, can divide metabolite excretion by creatinine excretion to compare collections | ||