Pediatrics: Vesicoureteral Reflux: Difference between revisions

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* '''VUR due to overwhelming the normal function of the UVJ'''
* '''VUR due to overwhelming the normal function of the UVJ'''
** May be of an anatomic or functional origin in the UVJ, bladder, or bladder outlet
** May be of an anatomic or functional origin in the UVJ, bladder, or bladder outlet
*Reflux is also considered secondary if its absence was documented at some point before its detection.


==== Causes ====
==== Causes (5) ====


*'''Bladder dysfunction'''
#'''Bladder dysfunction'''
**Can be of a congenital, acquired, or behavioral nature
#*Can be of a congenital, acquired, or behavioral nature
**Often the cause of secondary VUR
#*Often the cause of secondary VUR
* '''Posterior urethral valve'''
# '''Posterior urethral valve'''
** '''Most common cause of bladder outlet obstruction in infants'''
#* '''Most common cause of bladder outlet obstruction in infants'''
*** '''In females, anatomic bladder obstruction is rare. The most common structural obstruction in females is from a ureterocele that prolapses into the bladder neck.'''
#** '''In females, anatomic bladder obstruction is rare. The most common structural obstruction in females is from a ureterocele that prolapses into the bladder neck.'''
** Reflux is present in 48-70% of patients with PUV patients
#* Reflux is present in 48-70% of patients with PUV patients
* '''Neurogenic bladder'''
# '''Neurogenic bladder'''
** '''Spina bifida, in particular, is at risk for VUR'''
#* '''Spina bifida, in particular, is at risk for VUR'''
*** '''Special attention for the potential for occult spinal dysraphism is warranted during evaluation of any child with UTI'''
#** '''Special attention for the potential for occult spinal dysraphism is warranted during evaluation of any child with UTI'''
** '''Urodynamic risk factors for VUR:'''
#* '''Urodynamic risk factors for VUR:'''
**# '''Overactivity'''
#*# '''Overactivity'''
**#* '''Most common urodynamic abnormality associated with VUR in neurologically normal children'''
#*#* '''Most common urodynamic abnormality associated with VUR in neurologically normal children'''
**#* Overactive bladder frequently can be responsible for reflux
#*#* Overactive bladder frequently can be responsible for reflux
**# '''Inadequate or obstructive voiding patterns'''
#*# '''Inadequate or obstructive voiding patterns'''
**# '''Higher voiding pressures (may be due to inadequate sphincter relaxation)'''
#*# '''Higher voiding pressures (may be due to inadequate sphincter relaxation)'''
* '''Urinary Tract Infection'''
# '''Urinary Tract Infection'''
** UTIs and their accompanying inflammation can also cause reflux by:
#* UTIs and their accompanying inflammation can also cause reflux by:
**# Lessening compliance
#*# Lessening compliance
**# Elevating intravesical pressures
#*# Elevating intravesical pressures
**# Distorting and weakening the ureterovesical junction
#*# Distorting and weakening the ureterovesical junction
* '''Bladder and bowel dysfunction (BBD)'''
# '''Bladder and bowel dysfunction (BBD)'''
** In older children, acquired abnormalities in bladder and bowel function commonly known as bladder and bowel dysfunction (BBD'')'' have been associated with reflux
#* In older children, acquired abnormalities in bladder and bowel function commonly known as bladder and bowel dysfunction (BBD'')'' have been associated with reflux
*Reflux is also considered secondary if its absence was documented at some point before its detection.


== Grading VUR ==
== Grading VUR ==