Diagnosis and Evaluation of Adrenal Mass: Difference between revisions

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=== UrologySchool.com Summary ===
=== UrologySchool.com Summary ===


* '''<span style="color:#ff0000">History and physical exam</span>'''
* '''<span style="color:#ff0000">History and Physical Exam</span>'''
** '''Most patients are asymptomatic'''
**'''<span style="color:#ff0000">Screen for signs and symptoms related to disorders of</span>'''
*** '''<span style="color:#ff0000">Adrenal hyperfunction</span>'''
***# '''<span style="color:#ff0000">Hypercortisolism: classic symptoms of hypercortisolism, such as central obesity, moon facies, buffalo hump, facial plethora, menstrual disturbances, hirsuitism, proximal muscle weakness, easy bruisability, and abdominal striae, are nonspecific. Systemic manifestations include dyslipidemia, insulin resistance, and hypertension</span>'''
***# '''<span style="color:#ff0000">Hyperaldosteronism: hypertension</span>'''
***#*Hypertension classified as
***#** Elevated blood pressure: SBP 120-129 mm Hg; DBP < 80 mm Hg
***#** Stage 1 hypertension: SBP 130 - 139 mm Hg; DBP 80 - 89 mm Hg
***#** Stage 2 hypertension: SBP ≥140 mm Hg; DBP ≥ 90 mm Hg
***# '''<span style="color:#ff0000">Pheochromocytoma: headache, episodic sudden perspiration, tachycardia</span>'''
***# '''<span style="color:#ff0000">Adrenal sex steroid hypersecretion</span>'''
*** '''<span style="color:#ff0000">Adrenal malignancy</span>'''
* '''<span style="color:#ff0000">Labs (3)</span>'''[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147036/ §]
* '''<span style="color:#ff0000">Labs (3)</span>'''[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147036/ §]
*# '''<span style="color:#ff0000">Low-dose dexamethasone suppression test or 24-hour urinary cortisol to rule out hypercortisolism AND</span>'''
*# '''<span style="color:#ff0000">Low-dose dexamethasone suppression test or 24-hour urinary cortisol to rule out hypercortisolism AND</span>'''
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*#'''<span style="color:#ff0000">Unenhanced CT</span>'''
*#'''<span style="color:#ff0000">Unenhanced CT</span>'''
*#* '''<span style="color:#ff0000">If attenuation ≥ 10HU, obtain contrast enhanced CT with adrenal washout</span>'''
*#* '''<span style="color:#ff0000">If attenuation ≥ 10HU, obtain contrast enhanced CT with adrenal washout</span>'''
=== History and Physical Exam ===
*'''Most patients are asymptomatic'''
*'''<span style="color:#ff0000">Screen for signs and symptoms related to disorders of</span>'''
** '''<span style="color:#ff0000">Adrenal hyperfunction</span>'''
**# '''<span style="color:#ff0000">Hypercortisolism (9)</span>'''
**##'''<span style="color:#ff0000">Central obesity</span>'''
**##'''<span style="color:#ff0000">Moon facies</span>'''
**##'''<span style="color:#ff0000">Buffalo hump</span>'''
**##'''<span style="color:#ff0000">Facial plethora</span>'''
**##'''<span style="color:#ff0000">Menstrual disturbances</span>'''
**##'''<span style="color:#ff0000">Hirsuitism</span>'''
**##'''<span style="color:#ff0000">Proximal muscle weakness</span>'''
**##'''<span style="color:#ff0000">Easy bruisability</span>'''
**##'''<span style="color:#ff0000">Abdominal striae</span>'''
**##'''<span style="color:#ff0000">Systemic manifestations include dyslipidemia, insulin resistance, and hypertension</span>'''
**# '''<span style="color:#ff0000">Hyperaldosteronism: hypertension</span>'''
**#*Hypertension classified as
**#** Elevated blood pressure: SBP 120-129 mm Hg; DBP < 80 mm Hg
**#** Stage 1 hypertension: SBP 130 - 139 mm Hg; DBP 80 - 89 mm Hg
**#** Stage 2 hypertension: SBP ≥140 mm Hg; DBP ≥ 90 mm Hg
**# '''<span style="color:#ff0000">Pheochromocytoma (3):</span>'''
**##'''<span style="color:#ff0000">Headache</span>'''
**##'''<span style="color:#ff0000">Episodic sudden perspiration</span>'''
**##'''<span style="color:#ff0000">Tachycardia</span>'''
**# '''<span style="color:#ff0000">Adrenal sex steroid hypersecretion</span>'''
** '''<span style="color:#ff0000">Adrenal malignancy</span>'''


=== Labs ===
=== Labs ===