Stones: Epidemiology and Pathogenesis: Difference between revisions
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** Subjects who abuse laxatives are chronically dehydrated, resulting in intracellular acidosis. In addition, urinary sodium is low from sodium loss as a result of the laxatives. In this environment, urate preferentially complexes with the abundant ammonium rather than sodium and produces ammonium acid urate stones. | ** Subjects who abuse laxatives are chronically dehydrated, resulting in intracellular acidosis. In addition, urinary sodium is low from sodium loss as a result of the laxatives. In this environment, urate preferentially complexes with the abundant ammonium rather than sodium and produces ammonium acid urate stones. | ||
=== Medication associated stones === | === Medication associated stones[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1508366] === | ||
*'''<span style="color:#0000ff">Lotta Good Drugs Cause Calculi FIT TEST (12):''' | *'''<span style="color:#0000ff">Lotta Good Drugs Cause Calculi FIT TEST (12):''' | ||
*# '''<span style="color:#0000ff">L<span style="color:#ff0000">axatives''' | *# '''<span style="color:#0000ff">L<span style="color:#ff0000">axatives''' | ||