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  • 13:31, 9 December 2021 Urology4all talk contribs created page Prevention (Created page with "Chemoprevention 5-alpha reductase inhibitors (5-ARIs) Randomized trials (PCPT and REDUCE, see below ) evaluating 5-ARIs for prostate cancer prevention have found that their use results in ≈5% reduced risk of cancer Slight increased risk of high grade cancer Increased "risk" of high grade cancer is thought to be due to the higher probability of targetting a focus of high grade disease in a 5-ARI-induced smaller size gland PCPT (2003) Objective: determine whether a...") Tag: Visual edit