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  • 06:35, 17 December 2021 Urology4all talk contribs created page PSA and Other Markers (Created page with "== Blood based biomarkers (PSA, PSA-derivatives, PHI, 4Kscore, PSMA) == * '''PSA''' ** '''PSA Basics''' *** Discovered in 1979 *** '''Member of kallikrein gene family''' *** '''An enzyme (serine protease) which functions to liquify semen''' *** Molecular weight: 33-kD **** '''Begins as''' 17-amino acid chain '''preproPSA''' --> '''cleavage results in inactive proPSA --> cleavage''' by hK2 '''results in active form PSA''' *** Primarily produced by prostatic luminal epith...") Tag: Visual edit